Hyperpolarization of amino acid derivatives in water for biological applications.

Hyperpolarization of amino acid derivatives in water for biological applications† †Electronic supplementary information (ESI) available: Synthesis, para-hydrogen experiments, relaxation times of amino acid derivatives, catalyst decomposition and remarks on amino acid PHIP. See DOI: 10.1039/c5sc00503e

A Crystallization-Induced Asymmetric Transformation using Racemic Phenyl Alanine Methyl Ester Derivatives as Versatile Precursors to Prepare Amino Acids

L-Tyrosine and L-Dopa are the precursors in the biological synthesis of amine neurotransmitters. On the other hand, phenylalanine as an aromatic amino acid (AAA) is a precursor in the synthesis of L-Tyrosine and L-Dopa. For some substrates such as amino acids, resolution by the formation of diastereomers offers an attractive alternative. Among different methods in this case, crystallization-ind...

An Electrochemical Study of the S-Derivatives of 2-Amino Cyclopentene-1-Dithiocharboxylic Acid in Aqueous Ethanolic Media

A systematic study on the electrochemical behavior of the S-derivatives of 2-amino cyclopentene-1-dithiocarboxylic acid (ACDA) has been carried out in aqueous ethanolic solutions by means of polarography, coulometry and voltammetry. All the compounds studied exhibited a well defined anodic wave corresponding to a diffusion controlled process. Controlled potential coulometry gave n=1 per mol...

Isolation and Evaluation of Collagen from the Fish (Thunnus Tonggol) Skin: A Biological Material for Medical Tissue Engineering

Introduction: Collagen bears many applications in pharmacy and medicine, health and cosmetic products as well as food industry. In recent years, much attention has been paid to separation of collagen from marine organisms arising from the fact that its use in the diet is not restricted and triggers no risk of contagious diseases as well as religious restrictions. Moreover, fish collagen is uniq...

Synthesis of 2-Amino-4hydroxy-1H-Pyrrole-3-Carbonitrile from Glycine Under Microwave Irradiation

Reaction of Glycin with Malononitrile afforded respective Pyrrole. Pyrrole is one of the heterocyclic compounds with very important biological activities. Heterocycles are extremely important because of their wide range of applications that goes from their use as pharmaceuticals and agrochemicals to dyestuffs and additives. In this view, it was proposed to synthesize pyrrole-3-carbonitrile deri...